Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes
نویسندگان
چکیده
منابع مشابه
Genetic basis of male pattern baldness.
Common pattern baldness (androgenetic alopecia) is the most common form of hair loss in humans. In Caucasians, normal male hair loss, commonly known as ‘‘male pattern baldness’’ (MPB; MIM 109200), is noticeable in about 20% of men aged 20, and increases steadily with age, so that a male in his 90s has a 90% chance of having some degree of MPB. In addition to being among the most common natural ...
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Male pattern baldness can have substantial psychosocial effects, and it has been phenotypically linked to adverse health outcomes such as prostate cancer and cardiovascular disease. We explored the genetic architecture of the trait using data from over 52,000 male participants of UK Biobank, aged 40-69 years. We identified over 250 independent genetic loci associated with severe hair loss (P<5x...
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1 Chandler JR. Malignant otitis externa. Laryngoscope 1968;78:1257-94. 2 Chandler JR. Pathogenesis and treatment of facial paralysis due to malignant otitis externa. Ann OtolRhinol Laryngol 1972;81:648-58. 3 SchwartzGA, BlumenkrantzMJ, StudmakerWHL. Neurologiccomplicationsofmalignantotitis extema. Neuroloz 1971;21:1077-84. 4 Joachims HZ. Malignant external otitis in children. Arch Otola,yngol 1...
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15 صفحه اولMale pattern baldness and the risk of prostate cancer.
BACKGROUND Androgens play a role in the development of both androgenic alopecia, commonly known as male pattern baldness, and prostate cancer. We set out to study if early-onset androgenic alopecia was associated with an increased risk of prostate cancer later in life. PATIENTS AND METHODS A total of 669 subjects (388 with a history of prostate cancer and 281 without) were enrolled in this st...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1998
ISSN: 0022-202X
DOI: 10.1046/j.1523-1747.1998.00224.x